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Then decreased to involve a range of 4 to 108. Exp. 3. Prevention of ascariasis by feeding pyrantel did not increase P .10 ; ADG or ADF and it did not improve P .10 ; F G in the first 28 and first 70 d of the experiment table 4 ; . Treatments did not differentially affect P . 10 ; ADG or ADF for the 119-d period; however, F G was improved P .05 ; by pyrantel feeding early in the growing-finishing period treatment 2, 3 and 4 ; . On 70, livers of control pigs were severely scarred by ascarid larva migration, whereas livers of pyrantel-treated pigs had only a few lesions. The average number of lesions per 36 cm 2 liver surface was 31 for control pigs and 2 for pyrantel-treated pigs. Only one ascarid was found in the intestinal tract of one of the three control pigs killed on d 70. At 101 kg body weight liver ascarid scores were similar among treatments, however, scars on the liver surface were most numerous P .01 ; among pigs that had pyrantel removed or reduced in level at d 70 treatments 2 and 3 ; . The liver lesions found in pigs of treatment 3 suggest that 26.4 ppm pyrantel was insufficient to prevent ascarid migration. Intestinal ascarids were collected from 14 pigs at slaughter two pigs from each pen of replication 1 and 2, except that treatment 4 was no t represented in replication 2 ; . Ascarids were found in 3, 1 and 0 pigs of treatments 1, 2, 3 and 4, respectively, and the average number of ascarids found in pigs of treatment 1 was greater P .05 ; than in pigs of treatments 2, 3 and 4. The incidence of ascarid eggs in feces was extremely low, except in feces of control pigs sampled on d 63 and d 118. Averaged over collection periods, more P .05 ; ascarid eggs were shed by pigs of treatment 1 than by pigs of treatments 2, 3 and 4. Ney from excreting salt and water" although later revising this opinion in 1961 when he wrote: "it is improbable that the changes are primarily dependent on renal factors since they were also seen in some cases wvhere the blood-pressure decrease was negligible."" Some of the authors quoted have divided their treated patients into fluid-retaining and nonfluid-retaining groups and looked for differences between them to explain their different responses. These comparisons have usually been between small groups of patients and, partly for this reason, no convincing or consistent conclusions have emerged. The objective of this study was to determine the influence of LTP I on the plasma lipoprotein distribution of CSA. Our data suggests that LTP I appear to have a direct role in the distribution of CSA among plasma lipoproteins. This is similar to our observations with AmpB Wasan et al., 1994; Wasan and Lopez-Berestein, 1995 ; . However, unlike AmpB, the transfer of CSA between HDL and LDL appears to be only partially dependent on LTP I-facilitated transfer of CE. We have previously demonstrated that the distribution of AmpB among HDL and LDL after incubation in human plasma is facilitated by LTP I. However, once AmpB was incorporated into liposomes composed of negatively charged and neutral phospholipids, the ability of LTP I to transfer AmpB and 3H-CE from HDL to LDL diminished Wasan et al., 1994; Wasan and Lopez-Berestein, 1995 ; . We concluded from these studies that because AmpB interacts with free cholesterol and CE upon incubation in plasma Wasan et al., 1993; Bolard et al., 1980 ; , LTP I's ability to transfer AmpB between HDL and LDL was due to its ability to transfer CE between HDL and LDL and not due to the direct transfer of AmpB between lipoprotein fractions. In the case of CSA increases in LTP I concentration resulted in an increased percentage of CSA recovered in the HDL LPDP fraction during short-term incubations fig. 1 ; . As LTP I is the protein which catalyzes the transfer exchange of CE from CE-rich lipoproteins HDL and LDL ; for TG from TG-rich lipoproteins VLDL ; , these findings suggest that CSA plasma distribution may be related to its lipoprotein-lipid content. In experiments that were designed to directly measure the potential role of LTP I to facilitate CSA transfer, LTP I-mediated percent transfer of CE among HDL and LDL particles.

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5. Collins MH, Moessinger AC, Kleinerman J, et al. Fetal lung hypoplasia associated with maternal smoking: A morphometric analysis. Pediatr Res 19: 408-412, 1985.

Values are expressed as means SE; n 5-6 animals per group. TPN, total parenteral nutrition; R, resection; T, transection. Means with different superscripts are significantly different based on oneway ANOVA and protected least significant differences LSD ; . Results of the two-way ANOVA indicate significant interaction p 0.05 ; for resection and method of feeding such that the amount and location of apoptosis in the jejunal crypt were reduced by resection in TPN but not orally fed rats.

Preface.- A Tour through Networking and Grids.- Fundamental Stochastic Models.- Queuing Models.- Fundamental Deterministic Algorithms.Divisible Load Modeling for Grids.- Appendix A: Summation Formulas.- References.- Index and pyrimethamine.

Study population This study was designed to evaluate the effects of vaginal micronized progesterone on bleeding following HCG administration in IVFICSI procedures. A retrospective analysis was conducted of the computerized medical records of 149 consecutive women who had undergone ICSI between January 1 and April 30, 1996. Women were eligible for review if they had completed a routine assisted reproductionICSI procedure [using `long-protocol' stimulation with buserelinhuman menopausal gonadotrophin HMG ; within the specified time period] and had received vaginal micronized progesterone for luteal phase supplementation without oestrogen or HCG supplements. No restrictions were placed on age, weight or the subsequent outcome of the assisted reproduction procedure. Collection of information on bleeding pattern During the luteal phase all patients were systematically instructed to have routine contact by telephone with the nursing staff to enquire about their hormonal profile, to report on eventual side-effects and to state whether any abnormal vaginal bleeding had occurred. The data were recorded in writing from the telephone conversation directly onto the patients' individual charts kept in the laboratory and were then transferred to a computer operator to input. In the third week after oocyte retrieval, all patients were contacted by a senior scientist to receive their instructions on eventual follow-up of pregnancy, and in cases of no pregnancy, the first day of the menstrual bleeding was also notified. Treatment protocol Women whose charts were reviewed for this study had been allocated to ICSI for two reasons: a partner with a low sperm count defined as 500 000 progressively motile spermatozoa in the total ejaculate ; or failure on at least two previous IVF attempts defined as 5% fertilization ; . All patients were stimulated with a GnRH agonist desensitization buserelin; Hoechst AG, Frankfurt, Germany ; protocol in combination with an HMG step-up stimulation. When serum oestradiol reached a concentration corresponding to 200400 ng l for each medium or large follicle mean diameter 14 mm ; , an i.m. ovulatory dose of HCG 10 000 IU ; was given and buserelin was discontinued. Determinations of plasma -HCG and oestradiol 17-oestradiol ; were made on days 12 and 15 following embryo transfer i.e. 16 and 19 days after HCG administration ; . Vaginal micronized progesterone 200 mg three times daily in soft gelatin capsules; Piette Pharmaceuticals, Brussels, Belgium ; was begun on the day before oocyte retrieval and continued until the second -HCG determination even if early bleeding was noted. If -HCG was positive, vaginal progesterone was maintained until week 10 of the pregnancy.

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291 the dose of 0.1 mgkg-1 of body weight, had no effect. Only application of albendazol in a paste form consisting of 333 mg in 1 ml ALBAZOL ; , which was given to the affected cats during four days at the dose of 1 ml per 5 kg of body weight, was fully effective. The application itself as well as tolerance of this treatment was without any problems. On coprology during the third to fourth day of treatment, Dicrocoelium eggs in intensity of 1-2 were still found. The eggs completely vanished in all cats 3 to 4 days after finishing the treatment. We were not able to detect any eggs even after a longer interval of about one month to three years. In a week after finishing the albendazol treatment, the inflammatory changes of conjunctiva began to recede and the protrusion of the third eyelid was diminishing and in 2 cats after 14 days, and in 1 cat after 3 weeks, it disappeared completely. Shortly after the end of treatment as well as 10-14 days later, the appetite of all cats improved. In about a month the nutritional status of the cats returned to normal. There were other 12 cats in which the clinical manifestation was similar to that in the three cats mentioned above. We were, however, unable to obtain faeces for examination from any of these patients. When the symptomatic treatment, including control of common parasitic infections, remained ineffective and the described clinical status, the changes of the eyes, in particular, persisted, we treated these cats for four days with albendazole and in 9 cases there was a complete cure within the same period as in the three patients with confirmed dicrocoeliosis. Dicrocoeliosis in dogs During 34 years of practice in Zziwil, we were able to find Dicrocoelium eggs using coprology in 377 dogs. Different breeds were affected. Most of them were from the closest vicinity of our practice, where the infestation of the main hosts for this parasite i.e., cattle, sheep, goats, horses, rabbits ; was severe. We assumed that, with the known coprophagy of dogs, it is a secondary passage of eggs due to feeding on faeces of infected hosts. It was fully confirmed in 294 dogs because of negative subsequent coprological results. In other dogs, in which excrements for subsequent examinations were not available, the clinical status proved that findings of those eggs could have been associated with the infection of the dogs. At the beginning of 2001 in a short time period, we managed to identify and observe two cases of dicrocoeliosis in the dogs. Other six cases were identified until the end of 2004. The infection of all 8 dogs was confirmed by the first finding of Dicrocoelium eggs in the intensity of 1-3 and the subsequent examinations resulting in the same findings. Five dogs were born and reared in Switzerland, three were imported as puppies from the Czech Republic. Considering the fact that those three dogs were several times examined with negative coprological results right after their import, we may assume that they became infected with Dicrocoelium in Switzerland. The clinical manifestation of dicrocoeliosis in all dogs was characterised by alteration of the digestive apparatus. Dogs suffered from changes in the peristalsis, vomiting, diarrhoea, colic states, heavy pains and distinct subicterus. Skin lesions were apparent in four patients pruritus, eczemas, alopecia, interdigital dermatitis ; . Half of the clinically sick dogs quickly lost weight, temperament and working performance. The therapy of dicrocoeliosis was based on our experience with treating cats. Only repeated therapeutic doses of the effective drug can lead to permanent recovery. Albendazole was used in 6 dogs, and praziquantel in 2 dogs. We administered albendazole in a paste containing 333 mg in 1 ml like in the cats - ALBAZOL ; . We administered it by oral route at the dose of 1 ml per 5 kg of body weight and day during 4 to 5 consecutive days. For the treatment with praziquantel we used the Drontal plus tablets containing 50 mg of praziquantel + 50 mg of pyrantel + 150 mg of febantel in one tablet. Two tablets per 10 kg of body weight for four days were administered to two dogs. Treatment was started in these dogs soon after the appearance of clinical symptoms and all of them made a full recovery and questran.

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8: 52AM FD.00005 Capillary instabilities of liquid films inside a wedge , LI YANG, G.M. HOMSY, Department of Mechanical Engineering, University of California Santa Barbara -- We consider a liquid meniscus inside a wedge of included angle 2 that wets the solid walls with a contact angle . The meniscus has a convex interface which satisfies 2 + . The capillary pressure gradient due to a small disturbance in the location of the contact line moves fluid from a neck region to a bulge region, causing instabilities. A dynamic contact-line condition is considered in which the contact angle varies linearly with the slipping speed of the contact line with a slope of G: G represents perfect slip and fixed contact angle. A nonlinear thin film equation is derived and numerically solved for the shape of the contact line as a function of parameters. The result for G 0 shows that the evolution process consists of a successive formation of bulges and necks in decreasing length and time scales, eventually resulting a cascade structure of primary, secondary and tertiary droplets. When G 0, there is a similar but slower nonlinear evolution process. The numerical results agree qualitatively with very recent experimental results. 9: 05AM FD.00006 Three-dimensional coherent structures of surface turbulence , SERAFIM KALLIADASIS, Department of Chemical Engineering, Imperial College London, London SW7 2AZ, UK, EVGENY A. DEMEKHIN, EVGENY N. KALAIDIN, S.YU. VLASKIN, Kuban State University, Southern Research Center of Russian Academy of Sciences, Stavropolskaya St. 149, Krasnodar 350040, Russia -- The evolution of naturally excited disturbances on a thin liquid film falling down an inclined planar substrate undergoes several transitions between different wave regimes starting from two-dimensional 2D ; solitary pulses at small Reynolds numbers to the `surface turbulence' stage for sufficiently large Reynolds numbers where the surface is randomly covered by localized three-dimensional 3D ; coherent structures. Here we analyze the instability of 2D pulses to 3D disturbances and the transitions of 2D pulses to fully developed 3D waves. The main instability mechanism is the Rayleigh instability of well- separated isolated ; 2D solitary waves. On the other hand, the physical mechanism for the 3D instability of 2D periodic waves is due to wave-wave interaction and mass exchange between neighboring waves. These instabilities are characteristic of small inclination angles but under special conditions can be realized for the vertical flow. 9: 18AM FD.00007 Three-dimensional oscillatory large-scale Marangoni convection in a binary liquid layer1 , ALEXANDER NEPOMNYASHCHY, SERGEY SHKLYAEV, ALEX ORON, Technion - Israel Institute of Technology -- Marangoni. Table 1 Inequality and Economic Growth Within the OECD Dependent Variable: 20 year growth rate Estimation Method Mean Initial GDP per capita Initial Gini Ratio of Inequality 8, 436 0.325 OLS 1 ; -2.52 -6.25 ; -0.027 -1.397 ; 0.469 1960-1990 23 Random Effects 2 ; -2.94 -13.56 ; -0.029 -2.28 ; 0.595 1960-1990 23 Fixed Effects 3 ; -2.40 -2.57 ; -0.047 -1.74 ; 0.377 1960-1990 23 and quinidine.

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Editor--In their letter about the APHEA project's results on the effects of particulate matter and sulphur dioxide on mortality, 1 Bobak and Roberts proposed that heterogeneity in the observed effects between eastern and western European cities could be explained by differences in average winter temperature.2 They have calculated Spearman rank correlation coefficients to illustrate this association.
Sin-aldosterone system by reducing both renin14 and aldosterone15 release. Therefore, increasing the circulating concentrations of ANP through inhibition of NEP is an attractive therapeutic approach to a number of cardiovascular diseases such as hypertension and heart failure.16 However, although NEP inhibitors increase circulating ANP concentrations in humans and cause the expected natriuresis, 10, 1719 they do not generally lower blood pressure in normotensive subjects.10, 18, 20, 21 Indeed, both candoxatril22 and candoxatrilat23 have been reported as raising blood pressure in normotensive subjects. Although NEP inhibitors have been reported to lower blood pressure in patients with essential hypertension, 24 31 this finding has not been universal.19, 3235 Thus, the therapeutic value of NEP inhibitors in hypertension remains uncertain. In patients with heart failure, these agents do not reduce afterload although they do reduce pulmonary capillary wedge pressure, presumably because of natriuresis.17, 36 and qvar. One cycle versus repeated cycles with HIDAC was not examined. Due to this heterogeneity in autografts, Ara-C dose, and number of HIDAC cycles, we think that the data in the EBMT study should be interpreted with care. The EBMT study concluded that HIDAC should be avoided prior to autotransplantation because this treatment had "a major disadvantage of prolonging the delay to platelet recovery compared with standard-dose Ara-C." This delay was observed by Bishop et al. [4] who combined HIDAC with etoposide and daunorubicine but, despite the delay, HIDAC was associated with a significantly higher AML-free survival. In the study reported by Mayer et al. [3] HIDAC was used alone, and no major difference in the percentage of courses requiring platelet transfusions was detected when comparing Ara-C 3 g m2 86% ; and 400 mg m2 80% ; . The time until platelet recovery was not given in a randomized study by Kern et al. [5], but these authors also reported that recovery from critical cytopenia did not differ between patients treated with mitoxantron combined with Ara-C 3 g m2 and 1 g m2. Furthermore, hematopoietic reconstitution is usually observed within an acceptable time period for most patients transplanted with PBSC mobilized by HIDAC plus growth factors, although the initial studies suggest that late platelet reconstitution remains a problem for a minority of patients [1]. Thus, in our opinion the question of platelet reconstitution should not be decisive when considering the use of HIDAC together with autotransplantation in future clinical trials.

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For all courses offered in the Americas, except where noted by footnote, more information and registration can be obtained by phone or fax, through USP's Customer Service group. Phone: 1-800-227-8772, choose option 3, then option 4, Fax: 1-301-816-8148. Customer Service Representatives may also be reached at custsvc usp If you have questions on specific course content, please contact Kathy Muenchow at 301-816-8589 or PharmacopeialEducation usp . 1. For registration information, contact ventas proquifa .mx. One short-term human study examined the effect of 600 mg day of IP on accelerated bone loss caused by Paget's disease, a genetically linked bone disease characterized by skeletal deformity and bone pain. Paget's disease of the bone, breast cancer and prostate cancer have many endocrinologic and morphologic features in common. Sixteen patients with active Paget's disease were given either 1, 200 mg IP a day in four divided doses for one month and then a month of 600 mg day of IP in three divided doses, or the reverse, with a 15-day "washout" period in between. Both doses suppressed bone pain and BRM. The 1, 200-mg daily dose regimen more significantly reduced bone pain.13 Clinical trials of high dose IP 1200 mg per day ; should be considered for treating the bone pain of prostate and breast cancers and rapamune. The frequency analysis of a multi-rate system implies the conversion of the sampling rates of the discrete signals involved. The signals can be converted using multi-rate signal processing techniques - interpolators and decimators - described in the following [23]. The process of sampling a continuous signal x t ; using an ideal sample and hold device is assumed to be uniform, occurring h time apart. A sequence x kh ; results, referred to as x when only one rate is used. In order to be able to reconstruct the band-limited signal x k ; , the sampling period h should be chosen to satisfy the Nyquist sampling theorem. The process of digitally converting the sampling rate of a signal from a given rate F 1 h called sampling rate conversion and takes the name of interpolation if F F and decimation if F F The rate conversion system, given an input signal x k ; , outputs a signal y m ; with a new sampling rate F 1 h the following it is assumed that the sampling periods of the input and output signals are related by a rational fraction h F M Systems that can perform such rate conversion are linear time-varying discrete systems where the output y m ; at instant m is the response to an input at the time expressed as y m and pyrantel.
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Yildiran, S. T., Fothergill, A. W., Sutton, D. A. & Rinaldi, M. G. 2002 ; . In vitro susceptibilities of cerebrospinal fluid isolates of and raptiva.

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