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Publication Year Document Title Authors Journal Title 2004 2005 total 2002 Infection in Thai patients with systemic lupus erythematosus : A review of Wongchinsri J., Osiri M., Journal of the Medical 1 0 2 2003 SLE and infections Zandman-Goddard, G., Shoenfeld, Y. hospitalized patients Deesomchok U., Tantawichien T., Association of Thailand Clinical Reviews in Allergy and Immunology 25 1 ; , pp. 29-39 Akkasilpa S. 2002 Streptococcus suis infection in Thailand Vilaichone R.-K., Nunthapisud P., Journal of the Medical 2 Vilaichone W., Wilde H. Association of Thailand 3 2 Current diagnosis and treatment of infective endocarditis Tak, T., Dhawan, S., Reynolds, C., Shukla, S.K. Expert Review of AntiInfective Therapy 1 4 ; , pp. 639-654 2003 A Japanese case of Streptococcus suis meningitis associated with lumbar epidural abscess Ibaraki, M., Fujita, N., Tada, M., Ohtaki, O., Nagai, H. Clinical Neurology 43 4 ; , pp. 176-179.
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P053. Comparison between testicular sperm extraction using the BIP biopsy gun and micro-epididymal sperm aspiration to obtain spermatozoa from azoospermic men undergoing ICSI Cullinan R.T., de Boer K.A., Persson J., Bowman M.C., Jansen R.P.S. and Mortimer D. Sydney IVF, 4 O'Connell Street, Sydney, NSW 2000, Australia Introduction: The use of micro-epididymal sperm aspiration MESA ; combined with ICSI has proved successful in men suffering absence of the vas deferens or complete ductal obstruction. Testicular spermatozoa differ from those obtained from the epididymis in that they have not encountered the epididymal environment where sperm motility is considered to be acquired. However, testicular sperm extraction TESE ; by biopsy provides a simpler surgical method of obtaining spermatozoa and is of importance when spermatozoa cannot be obtained from the epididymis. Here we report successful retrieval and fertilization with ICSI using testicular spermatozoa and a pregnancy rate comparable with MESA ICSI. Materials and methods: Testicular tissue samples 15 or 22 length and 1 mm in radius were obtained using the BIP High-Speed Multi Biopsy System and placed in 5 ml HEPES-buffered human tubal fluid supplemented with 10 mg ml human serum albumin. In each case, two punctures were taken from one testis. The tubules were separated with fine needles and their contents allowed to diffuse into the medium. The resulting suspension was then left at 37C for several hours until injection. The suspension was centrifuged at 200 g for 5 min and the supernatant removed. Motile spermatozoa from the pellet, or in some cases spermatozoa teased from.
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Producing fuel ethanol, but such policies could change. 4 ; Basic research pressures -- Significant industrial and practical technologies result from the search of basic science for truth and discovery. These "just because it's there" discoveries often lead to huge advances or potentially impactful advances. Examples include polymerase chain reaction PCR ; technology, which was designed for multiplying minute quantities of genetic information for research purposes but is now employed to produce useful genetic libraries for plant, animal, and microbial species or for forensic diagnostics. DNA sequencing was designed to help researchers decode genetic information, but with the advent of improved methods, the sequencing of the human genome and other important crops and species could lead to new health therapies or improved crop production. Genetic engineering was initially formulated out of a desire to understand how to transfer genetic information amongst similar microbial species. Now it is used to produce life-saving therapeutics such as insulin or human growth hormone, but can also be used to increase milk production in cows, manufacture new polymers, or develop new therapeutics. The following recasts these drivers in an outline that displays some of the specific aspects of each of the drivers.
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TTP LabTech UK ; have announced further expansion of its Custom Automation business. This follows six years of continuous growth annual turnover has grown over 24% a year compound ; and a doubling of staff numbers to enable faster delivery of innovative engineering to a broad spectrum of high profile clients. With unrivalled expertise covering engineering, software, physical and organic chemistry, and materials science, TTP LabTech boasts a team of exceptional calibre and is set to significantly broaden its global customer base. With 20 years' experience developing novel technologies, TTP LabTech's custom automation business provides practical and innovative integrated automation across a number of industry sectors. Core skills of process automation, liquid and solid handling, and manufacturing scale-up have made TTP LabTech a particularly successful technology provider for the research and development section of the petrochemical market. Recent projects undertaken have involved automating the movement of volatile and viscous liquids, designing novel reaction vessels, and developing automated synthetic formulations and analytical platforms. Matthew Cook was recently appointed Commercial Development Manager, to further develop the custom automation business and address the increasing need for automation and development projects across numerous industry sectors, "We have always worked very closely with scientists and engineers to bring new and innovative technology to the market place, as evidenced by our strong product portfolio. We also manufacture our own products, so understand the need to develop systems that are simple to produce but robust in the field. Our multidisciplinary and highly skilled development team, have provided our partners with exceptional solutions to complex automation-based problems" He continued, "This experience and expertise has allowed us to apply our innovations across many new industry sectors such as the petrochemical market, in order to discover new and exciting challenges and colesevelam.
Author Disclosure Ms Charrois, Ms Hrudey, and Dr Gardiner did not disclose any financial relationships relevant to this In Brief. Dr Vohra has salary funding from Alberta Heritage Foundation for Medical Research and Canadian Institutes of Health Research.
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Juarrero, A 1999 ; . Dynamics in action: Intentional behaviour as a complex system. Cambridge, MA: MIT Press. Keesing, R. & Strathern, A. 1998 ; . Cultural anthropology: A contemporary perspective. Orlando, FL: Harcourt Brace. Nonaka, I. & Konno, N. 1998 ; . The concept of "Ba": Building a foundation for knowledge creation. California Management Review, 40 3 ; , 40-54. Nonaka, I. & Takeuchi, H. 1995 ; . The Knowledge-creating company. London: Oxford University Press. Snowden, D. 1999 ; . The paradox of story. Scenario and Strategy Planning, 1 5 ; . Snowden, D. 2000 ; . Organic knowledge management: Part I The ASHEN model: An enabler of action. Knowledge Management, 3 7 ; , 14-17. Stacey, R. D. 2001 ; . Complex responsive processes in organizations: Learning and knowledge creation. New York: Routledge.
Total porphyrin, especially PROTO excretion into the culture medium, increased with culture time and reached a maximum after 10 days, whereas intracellular accumulation of these metabolites was also found, probably due to saturation of the excretion processes. URO and COPRO especially isomer III ; are excreted in the urine, while PROTO and COPRO especially isomer I ; are secreted into the bile by nonvesicular carriers targeted to the canalicular domain of the plasma membrane Berenson et al., 1995 ; . In cultured hepatocytes, the secreted excreted products through sinusoidal and canalicular domains of the plasma membrane accumulate in the culture medium. Exposure to 3.9 M As III ; produced two opposite responses: whereas intracellular porphyrins increased with exposure time, extracellular porphyrins decreased as compared with unexposed cultures. The intracellular porphyrin accumulation in As III ; -exposed cultures is paradoxical, since a decrease in enzyme activities mostly PBG-D and UROIII-S ; was also observed. In vivo experiments have shown similar increases in total porphyrin content in the liver of As III ; -exposed mice Garcia-Vargas et al., 1995 ; . The paradoxical distribution of porphyrins in the cytosol and culture medium could be explained by an insufficient metabolic energy supply, since arsenic can inhibit the synthesis of ATP Gresser, 1981 ; . The activity of mdr2 P-glycoprotein, an ATP-dependent drug efflux pump, which has been implicated in hepatobiliary removal of the hydrophobic organic anion PROTO and biliary secretion of coproporphyrin I and III Beukeveld et al., 1996 ; , is inhibited by SH-oxidizing reagents Gatmaitan et al., 1994 ; such as and commit.
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