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AENEAS ENEAS AETHOW AFFLECK ACHENLEK ACHINFLECK ACHINLEK ACHITHELEGE ACHLEC ACHLECK ACHLEK ACHTINLEK ACHYNLEK AFFLECT AFLEK AGHELEK AGHLEKE AGHYNLEK AITHINLEIK AQUINLEK ATHELEK ATHINKEL ATHINLEIK ATHINLEK ATHLEK ATHLYK ATHYNLEK AUCHENLECK AUCHENLEK AUCHIMLEK AUCHINLEC AUCHINLECH AUCHINLEK AUCHINLOK AUCHLEC AUCHLECK AUCHLEK AUCHTLEK AUCHYNFLEK AUCHYNLEK AUTHINLECT AUTHINLEK AUUYNLEC AVTHINLECT AWCHINLECKE AWCHLEK AWQWHYNLEKE EFFLEK HAGHENLEK HAUCHYNLEK AFFROOD AFRICA AFFRICA AFFRICK AFFREKA AFFRICA AUFRIKE EFFRICK AGATE AGER AGNETIS AGNEW AGGNEW AGNEV AGNEWE ANGNEW D'AGNEAUX O'GNIVE O'GNEEVE AHILLO AHILLOW AICKLEY ACKLAY AICKLA AICKLAY compare to English ACKLEY ; AIKEN ACKIN ACKYN ACKYNE AICKEN AICKIN AICKINE AICKING AIKEIN AIKEYNE AIKIN AIKINE AIKING AIKNE AIKUN AIKYNE AITCKEN AITKANE AITKEN AITKENE AITKIN AITKINE AITKINS AITKYN AITKYNE AKEN AKENE AKIN AKINE AKYNE ATKIN ATKINE ATKINS ATKYN AUKIN AYKKYNE AYTKINE AYTKYN AYTKYNE ECKIN AIKENHEAD AICKINHED AICKINHEID AIKENHEID AIKINHEID AIKYNHEAD AITKENHEAD AITKINHEAD AITKYNHEID AKENHEDE AKHEID AKENHEAD AKINHEAD AKINHED AKINHEDE AKINHEID AKYNHED AKYNHEDE AKYNHEID AKYNHEUED AKYNHEYD AUCHINHEAD AUKINHEAD EAKINHEID AIKERS AICKERS AKIRRIS AKURIS AYKERIS AIKENSIDE AIKMAN AKEMAN AKMAN AKYMAN HEKMAN ACMAN AILMER AIMOIR ALMERE AYLEMER AYLMER ALNMER AIMERLAND AINLIE ANLEY AINSLIE AINSLEE AINSLEY AINSLOE ANENISLIE ANESLEI ANSLEE ANSLIE ANSLY ANYSLE AYNESLEY AYNESLEYE AYNISLE AYNSLE AYNYSLEY ENSLIE HANESLEJ HAYNISLY HENISLE HENESLEI AIR AIRE ARE AYR AYRE compare EYRE ; AIRD ARD AIRDS AIRIE AIRKIE AIRLAND AIRNES AIRRES AIRSTOUNE AIRTH AIRTHE ARTH ARTHE DERTH ERTH ERTHE HERTH AITH AITKINSON AIULF AIULFUS EYOLFUS AKINSTALL ALAN AILEN ALANE ALEN ALENE ALEYN ALLAN ALLAND ALLANE ALLEN ALLONE ALOWNE CALLAN CALLEN AILENE ALWYN ALAIN ALAMNVS ALANUS see Note 3 ; compare to ALMAN ; ALANE ALARD ALARDUS ALASTAIR ALASDAIR ALBANACH ALBENACH ALBERT ALBERTI ALBERTUS ALBURN ALBURNE ALCOCK ALKOK ALCORN ALCOIRNE ALCORNE ALDCORN ALDCORNE ALDYCORNE AULDCORN AULDCORNE AWLDCORN ALDAN ALDEN ALDIN see COSPATRIC ; ALDANSTON ALDINSTONE ALDINSTOUN ALDYNSTOUN HALDANISTUN HALDANSTONE HALDANSTOUN HALDENSTON HALDENSTONE HAWDENSTON compare to ALDINSTOUN ; ALDENGTON ALDERSTON ALDERSTONE ALDERSTOUN ALDERSTOUNE ALDIRSTOUNE ALDIE ALDINSTOUN ADINSTOUN ADNISTOUN ALDINSTON ALDINSTOUNE ALDSTON ALDSTONE ALDYNSTON AULDINSTOUN HADSTONE HALDSTON HALDSTONE HALTANSTANE ALDEN ALDYN compare to ALDANSTON ; ALDIRCH ALDIS ALDHOUS ALDHUS ALDOCH ALDHOCH ALDOCHT ALDOCK ALDOLF ALDOTH ALDOUGH AULDHOCHT AULDOCH AULDOCHT HALDHOCHT ALDOWY see MACILDOWIE ; ALDRED ALDREDUS ALDRI ALDREIS ALDROXBURGH ALEHOUSE AILHOUS AILHOUSS AILHOWS AILHOWSE AILLHOUSS ELEHOUS ALEXANDER ALASDAIR ALAXANDAIR ALECKANDER ALISANDRE ALISSCHONDER ALSCHINDER ALSCHONER ALSCHUNDER ALSHANDER ALSHUNDER ALSINDER MACALEXANDER M'ALASDAIR see ELSHENER and MACALASTER ; ALEXANDERSON ALEXANDERSOUN ALEXANDRI ALISTERSOUN ALLISTERSOUN ALEXSONE ALFORD ALFRED ALURED ALWREDUS AMFRIDUS ALGEO ALGIE ALGO ALGOE ALGOW ALJO ALLGEO compare to AULDJO ; ALICE ALISE ALICESON ALICE ALICIE ALIE ALLIE ALYE ALISON AILLIESON ALASON ALESON ALESONE ALESOUN ALIESONE ALIESOUNE ALISONE ALISSONE ALIZON ALLANSON ALLASON ALLASONE ALLASOUN ALLASOUNE ALLASSON ALLESON ALLESOUN ALLESOUNE ALLISON ALLISONE ALLSOUN ELISONE ".probably son of ELLIS, " ; compare to ELLISON" ALLANACH ALENACH ALLANACHE ALLANOCK ALLENOCH ALNACH CALLANACH ".probably descended from the MACALLANS of Macfarlane ." ; ALLANSHAW ALLANSCHAW ALLANSHA ALLINSHAW ELLENSCHAW HALLANDSCHAW ALLANSON ALANI ALANESONE ALANESOUN ALANI ALANSON ALANSONE ALANSOUN ALEINSON ALENSONE ALEYNSON ALEYNSSON ALLANSONE.
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Sir, Gemifloxacin is a novel antibacterial drug belonging to the quinolone class.1 Quinolones inhibit bacterial type II topoisomerases--DNA gyrase and topoisomerase IV. Fluoroquinolones containing 6-fluoro- and 7-piperazinylsubstituents, such as norfloxacin, ofloxacin and ciprofloxacin, preferentially inhibit Gram-negative bacteria. Derivatives such as sparfloxacin, grepafloxacin and trovafloxacin, containing in addition a 5-amino, 5-methyl or 7 ; substituent, respectively, show enhanced activity against Gram-positive bacteria. These preferences could be reflected in a higher affinity of the different drugs for the respective primary target of quinolone action, which is DNA gyrase in Gramnegative organisms and topoisomerase IV in Grampositive bacteria. As has been shown for Escherichia coli, a high level of fluoroquinolone resistance requires the stepwise acquisition of mutations in the respective genes of the A subunits of DNA gyrase gyrA ; and topoisomerase IV parC ; .2 Thus, to prevent development of resistance, the ideal quinolone would either act equally well against both targets or preferentially inhibit one target with high efficiency. Gemifloxacin carries a novel substituent at the C7 position of the 6-fluoro-1, 8-naphthyridone core, and has a broad spectrum of antibacterial activity against both Gramnegative and Gram-positive bacteria.3 To evaluate the antibacterial potency further, we determined the MICs of gemifloxacin, ciprofloxacin, sparfloxacin, pefloxacin, norfloxacin and ofloxacin for parental wild-type strains of E. coli, Staphylococcus aureus, Pseudomonas aeruginosa and corresponding single-step and multiple-step mutants carrying known resistance mutations in the target genes gyrA and parC grlA and in loci associated with reduced quinolone accumulation marR, nalB, nfxB and nfxC ; . Mutants of the E. coli wild-type strain were obtained and characterized as described previously.4 Mutants of S. aureus strain ATCC 6835 were kindly provided by Dr H.-G. Wetzstein, Bayer AG, Leverkusen, Germany. The P. aeruginosa parental strain, ML 5087, and its nalB and nfxB mutants were kindly provided by Dr K. Poole, Queen's University, Kingston, Canada. An nfxC mutant of ML 5087 was selected in vitro on agar plates containing chloramphenicol 1000 mg L and characterized by its resistance profile according to Khler et al.5 Drug susceptibilities were determined by the broth microdilution method according to NCCLS6 using Micronaut-S microtitre plates kindly provided by Merlin-Diagnostik, Bornheim, Germany. P. aeruginosa nfxB and nalB mutants did not grow adequately in MuellerHinton broth, so standard broth no. I Merck, Darmstadt, Germany ; was used instead for these strains. Mutation rates were determined by plating c. 10101011 cfu on agar plates containing the respective fluoroquinolone at a concentration of 4 MIC. The results of the MIC determinations are summarized in the Table. For P. aeruginosa wild-type strain ML 5087, MICs obtained with MuellerHinton and standard broth no. I were comparable within one serial dilution step ; . The mutation rates determined with E. coli wild-type were 1.2 1010 for gemifloxacin and 5 108 for ciprofloxacin, those with S. aureus ATCC 6835 were 1.2 108 for gemifloxacin and 9.2 108 for ciprofloxacin and those with P. aeruginosa ML 5087 were 1.6 108 for gemifloxacin and 8.2 108 for ciprofloxacin. Gemifloxacin had the highest activity of all the fluoroquinolones tested against the S. aureus wild-type strain. It was superior to pefloxacin, norfloxacin and ofloxacin for all three wild-type strains. It had comparable activity to sparfloxacin and ciprofloxacin for E. coli and was at least as effective as sparfloxacin but less active than ciprofloxacin against P. aeruginosa. Mutations affecting the respective primary target, such as the S83L mutation of E. coli gyrA and the S80F or E84K mutation of S. aureus grlA, affected the MIC of all six fluoroquinolones, but did not result in clinical resistance to gemifloxacin and sparfloxacin MIC 1 mg L ; . Mutations affecting the secondary quinolone target, such as a parC S80I mutation in a gyrA + background of E. coli and a gyrA S84L or E88K mutation in a grlAR background in S. aureus, resulted in an identical or lower MIC increase for gemifloxacin compared with the five other quinolones. The impact on the susceptibility of any of the three mutations in nalB, nfxB and nfxC associated with.
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Pados, G. and Devroey, P. 1992 ; Luteal phase support. Assist. Reprod. Rev., 3, 148153. Pados, G., Camus, M., Van Steirteghem, A. et al. 1994 ; The evolution and outcome of pregnancies from oocyte donation. Hum. Reprod., 3, 538542. Pellicer, A., Matallin, P., Miro, F. et al. 1989 ; Progesteron versus dehydrogesterone as replacement therary in women with premature ovarian failure. Hum. Reprod., 4, 777781. Powers, M., Schenkel, L., Darby, P. et al. 1985 ; Pharmacokinetics and pharmacodynamics with transdermal dosage forms of 17-estradiol: comparison with conventional oral estogens used for hormone replacement. Am. J. Obstet. Gynecol., 152, 10991103. Remohi, J., Vidal, A. and Pellicer, A. 1993 ; Oocyte donation in low responders to conventional ovarian stimulation for in vitro fertilization. Fertil. Steril., 59, 12081215. Renard, J. and Babinet, C. 1984 ; High survival of mouse embryos after rapid freezing and thawing inside plastic straws with 1, 2 propanediol as cryoprotectant. J. Exp. Zool., 230, 443448. Rosenwaks, Z. 1987 ; Donor eggs: their application in modern reproductive technologies. Fertil. Steril., 47, 895909. Rosenwaks, J., Navot, D., Veeck, J. et al. 1988 ; Oocyte donation: the Norfolk Program. Ann. N.Y. Acad. Sci., 541, 728741. Ryan, K. and Engel, L. 1953 ; The interconversion of estrone and estradiol by human tissue slices. Endocrinology, 52, 287291. Schiff, l., Tulchinsky, D. and Ryan K. 1977 ; Vaginal absorption of estrone and 17-estradiol. Fertil. Steril., 28, 10631066. Schmidt, C., De Ziegler, D., Gagliandi, C. et al. 1989 ; Transfer of cryopreservedthawed embyos: the natural cycle versus controlled preparation of the endometrium with gonadotropin-releasing hormone agonist and exogenous estradiol and progesterone. Fertil.
ATC cl J01MA ATC cl label Fluoroquinolones Included antibacterials + ATC code ; Ofloxacin J01MA01 ; , Ciprofloxacin Oral ; J01MA02 ; , Ciprofloxacin Parenteral ; J01MA02 ; , Pefloxacin J01MA03 ; , Enoxacin J01MA04 ; , Temafloxacin J01MA05 ; , Norfloxacin J01MA06 ; , Lomefloxacin J01MA07 ; , Fleroxacin J01MA08 ; , Sparfloxacin J01MA09 ; , Rufloxacin J01MA10 ; , Grepafloxacin J01MA11 ; , Levofloxacin J01MA12 ; , Trovafloxacin J01MA13 ; , Moxifloxacin J01MA14 ; , Gemifloxacin J01MA15 ; , Gatifloxacin J01MA16 ; Rosoxacin J01MB01 ; , Nalidixic acid J01MB02 ; , Piromidic acid J01MB03 ; , Pipemidic acid J01MB04 ; , Oxolinic acid J01MB05 ; , Cinoxacin J01MB06 ; , Flumequine J01MB07 ; Penicillins, comb. With other antibacterials J01RA01 ; , Sulfonamides, comb. excl. trimethoprim ; J01RA02 ; , Cefuroxime, comb. with other antibacterials J01RA03 ; Vancomycin Parenteral ; J01XA01 ; , Teicoplanin J01XA02 ; Colistin Parenteral ; J01XB01 ; , Polymyxin B Parenteral ; J01XB02 ; Fusidic acid J01XC01 ; Metronidazole Parenteral ; J01XD01 ; , Tinidazole Parenteral ; J01XD02 ; , Ornidazole Parenteral ; J01XD03 ; Nitrofurantoin J01XE01 ; , Nifurtoinol J01XE02 ; , Fosfomycin Parenteral ; J01XX01 ; , Fosfomycin Oral ; J01XX01 ; , Xibornol J01XX02 ; , Clofoctol J01XX03 ; , Spectinomycin J01XX04 ; , Methenamine, hippurate, J01XX05 ; , Methenamine, mandelate J01XX05 ; , Mandelic acid J01XX06 ; , Nitroxoline J01XX07 ; , Linezolid J01XX08 ; Amphotericin B J02AA01 ; , Hachimycin J02AA02 ; , Miconazole J02AB01 ; , Ketoconazole J02AB02 ; , Fluconazole J02AC01 ; , Itraconazole J02AC02 ; , Voriconazole J02AC03 ; Flucytosine J02AX01 ; , Caspofungin J02AX04 ; , Micafungin J02AX05 ; , Nystatin J02AX10.
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First Baptist Church south of Ellinwood. Eggers - Moore Doug Eggers and Sandy Eggers, both of Ellinwood, announce the engagement and approaching marriage of their daughter, Elissa Eggers, to Troy Moore, son of Mr. and Mrs. John Moore of Belle Plaine. The bride-elect is a 2001 graduate of Fort Hays State University with a bachelors degree in Sociology. She is employed by Center for Counseling as a childrens case manager. The prospective groom is a 2000 graduate of Emporia State University with a bachelors degree in health promotion and athletic training. He is employed by Healthsouth Sports Medicine and Rehabilitation in Great Bend. The wedding is planned for Feb. 22, 2003, at St. John Lutheran Church in Ellinwood. McFarren - Bailey Carol Everett of Great Bend and Curtis McFarren of Hays announce the engagement of their daughter, Aimee McFarren, to Chance Bailey, son of David and Jamie Bailey of Ellinwood. The bride-elect is a graduate of Great Bend High School and is employed by Credit Union of America. The prospective groom is a graduate of Great Bend High School and is employed by Larned Correctional Mental Health Facility. The wedding is planned for May 10 at Trinity Lutheran Church in Great Bend. January 4, 2003 Kizzar -- Wirtz Kendra Kizzar of Chase and Ryan Wirtz of Ellinwood announce their engagement. Parents of the couple are Nancy and Doug Kizzar of Chase and Debbie and Jerry Wirtz of Ellinwood. The wedding is planned for May 29 at St. John Lutheran Church in Ellinwood. The bride-elect will graduate in May from Fort Hays State University with a bachelor of science degree in nursing. The prospective groom attended Northwest Kansas Technical School in Goodland and is an electrician at North American Salt Company in Lyons.
LOOK AT THIS. This Harry Potter pillow creation by Jane Alvarez is just one of the many great items you will find at our Preview and Annual Sales. We will also have a beautiful patriotic quilt made by Anne Marsh. There will be many unique and beautiful gifts for everyone on your Christmas list, birthday list, whatever the occasion. Mark your calendar now and please come to either or both ; of our sales events. Friday, Oct 4th, 5: 30-7: Sat, Oct 5th , 10: 00 AM-3: 00 Both events take place at Christ Lutheran Church, 829 William Hilton Parkway. All proceeds are donated to Hospice Care of the Lowcountry. The Craft Group has donated more than , 000 to this charity. Pine Cone Picker-Uppers are still available for .00 each. There is no easier way to clear your lawn of the multitude of pinecones that fall at this time of year. To order, please call Darlene Yates, 681-6137. NEEDED: Old costume jewelry. Again, please call Darlene. And, thank you to those who have responded so generously to our requests for items we need to complete some of our projects and guanethidine.
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Figure 1 Helical dynamic abdominal CT revealing a liver tumor with a maximum diameter of 5.2 cm in segment 8 A ; and abdominal angiography showing hypervascularity in it B.
A c a party, open t o till Democ r a t the borough, w a s held liy tlio -JCalr -Ha-veuBComcn H JDfimoC ratio club a t American Mechanics hall on P a Haven road, Friday night, Mra Charlotte Robertson, county commlttee-wonmn, addressed t h e guest * a n d congratulated t h e their organ IMUon, A. door-stop donated by Mrt, Harold Conk of R e Bank, w a s disposed of a n won by Mrs. Julia Sweeney of F a Haven. M rs . William T u r lor of R e gave solo a n d received much applause. E i g now members were admitted * Mrs. R i c McAllister, M r s. B , PUBLIX Pryor, Mrs, Olive Herald, Mrs. J * J * Lynch, Mrs. M * McNally, Mrs\ G. Turner. Mrs * Harold Conk a n d Mrs. M, Weber. T h e individual table prizes werfl hammered b r a dinner gongs. Refreshments were served. T h o attending other t h a those Stntt 3 * 30 * T, O 1000 mentioned were Mrs. Victor Wolf- Satttrdaya a n d Holidays Continuous kamp, Mrs. Julia Kniffln, Mrs. George t eWinne # Miss M a r Felsman F M r Feters. Mrs, H a r 1 TIMES TODAY I vey Tilton, Mrs. J o h FhlefrenberF d . t 23. 7iSK, e: 4& ger, Mrs. John Mulvlhlll, Mrs. Walr: CHARIX3 KARREIX t e r Connor, Mrs. Clarence Legg. MADGE EVAN3 Mrs. George Hawkins, J r . , Miss In Mary 36oyle# M r s . Chaunzy. "HEAETDREAK" Mro. Irving VAnBruiit, Mrs. Thomas Donahuo, Mrs. Anna Donahue, Mrs. J. Wolcott, Mrs. O. E . Harrison, Mrs. J . Spiltane, Mrs. JM. Lenkuhl, TOMORBOW a n d VBmKY Mrs. G, Handy. Mrs. G, Fltzpatrltilt, FeAtutu . t 3: 20, 7: D; 49 Mrs, B Fryor. Mrs. J . Fryor, Mies Nan Mflhoti, Mr. a n d Mrs. H a r Chlvalrau. Dandlt. SmoCk. Miss Sarah Murphy, AlexanI""! Alwnjr * 1 iininnmntl--.\cvtr der Doughty, Mrs, R . VanBrunt, 1 l l l Mrs. E . Goode-nough, Miss M&rlon H a r m , Mrs. George H a r Mrs, R. F lulder, Mr * ?. K. Merriman, Ml"33 Mary CoIIlna, Mlss Xjuella Jeffrey, MIBS Margaret Tobln, M. E a g en. M r s , Ulcnnor Garvey. Mi'js May Porter. Mrs. Wilbur Smith. Mrs Raymond McCue, Patrick McCuo. Mr. a n d Mrs. J , Moilci, M r s , Agnca FetrQae * Anthony Martin, Mrs. Boss Dennl&ten a n d Miss Margaret Man * n& * MeotingB will be held t h e first and third Fridays of each month a t Amerleaii Mechanics hall In F a HENRY'S Haven, T h e n meeting will he F r night of this week. Rorncmfle and guarana.
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TAMPA CONTINUED Edward Friscia 813-286-0315 A, E, F, H, K, L, M, N, R, S, T, U, V, W Foreign language - Spanish Elliot Goldstein 813-810-1500 B, C, J, J1, J2, J3 L, M, N, R, S, T, U, V, W Perry Gruman 813-870-1614 A, E, F, G, H, K, L, N, O, R, S, T, U, V, W Foreign language - Spanish Victoria Holmberg 813-281-0103 C, E, F, G, H, N F. Lorraine Jahn 813-225-1818 A, L, O, T, W Scott Jeeves 813-254-3533 Q Joseph Kalish 813-962-8685 C, K, L, M, N, T, U, V, W C. J. Keel 813-282-3858 C, K, N, O, Q, T, U, V, W James La Russa 813-251-1411 F, K, N, Q, R, S, T, U, V, W Lawrence Lempert 813-935-2162 A, D, G, I, K, L, N, O, R, S, U, V, W Starlene McGory 813-932-3477 D, F, G, H, N, O, Q, W Ashley McCorvey Myers 813-839-7440 A, F, N, R, S, W Byron Nenos 813-264-7929 A, C, Q, T, U, W Foreign language - Greek Sheila Norman 813-251-6666 A, J2, L, N, R, S Carl Ohall Alfonso And Ohall, P.A. 813-258-5400 B, Q, T, U, W Laurie Ohall 813-250-6252 R, T, V, W Gerald Perez 813-832-1888 A, E, F, G, H, Q Thomas Rutherford 863-256-4030 K, L, N, O, T, U, V, W Neil Schecht 813-353-9500 K, W L. David Shear 813-222-6610 K, T, U, W Timothy Sierra 813-258-3455 A, Q William Thornton 813-969-2300 L, N, Q, R, S, T, U, V, W David Thorpe 813-933-5051 A, K, L, O, T, U, W Keith Warshofsky 813-636-8886 E, F, G, H, T, U, W Joanne Wilburne 800-298-1112 A, K, T, W Foreign language Spanish WESLEY CHAPEL Jacob Reiber 813-973-0883 D, H, K, L, N, O, T, U, V, W Foreign language German, Yiddish ZEPHYRHILLLS Nancy McClain Alfonso McClain And Alfonso 813-782-8700 A, C, K, L, M, N, R, S, T, U, V, W Foreign language - Spanish.
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The low elongation at break and lower impact strength Izod test ; of the modified samples after irradiation is caused not only by the higher crystallinity stimulated by the nucleating agent, but also by the destruction of polymer chains initiated by radiation. This means that addition of DMDBS did not influence the formation of radicals and their deactivation. In the future this leads to the addition of some radical scavengers and antioxidants. Conclusion The obtained results may lead to the conclusion that the addition of DMDBS leads to improv.
The Investors' Statement was issued in support of the Extractive Industries Transparency Initiative EITI ; , which was formally launched by UK Prime Minister Tony Blair in June 2003. The EITI is a multi-stakeholder initiative led by the UK government that seeks to establish common standards for reporting taxes, royalties and other payment flows between oil and mining companies and their host governments. The purpose is to lessen the opportunities for such monies to go missing, given that billions have vanished from government coffers in recent years, even as living standards, economic and social stability and the local investment climate have continued to deteriorate and halofantrine.
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Cluding viral infection, vascular insult, perilymphatic hypoxia, intralabyrinthine membrane rupture, and inflammatory and metabolic causes, but none has been shown to cause all, or even most, cases of SSNHL.1 And there is not even universal acceptance of a standard definition of SSNHL.1 Thus, treatment of SSNHL cannot be established until the pathogenesis of this condition is clarified.1 Only corticosteroid therapy was reported to be effective for SSNHL in a prospective, randomized, placebocontrolled study.4 However, several studies5-7 reported that corticosteroids were ineffective for SSNHL. Therapeutic methods, especially medication with corticosteroids combined with some vasodilators, diuretics, histamine, plasma expander, carbogen inhalation, and or calcium channel blockers, have been attempted.1, 2 At Toyooka Hospital, patients with SSNHL, irrespective of the type of hearing loss, had been treated with a combination of corticosteroids, adenosine triphosphate disodium, vasodilators, and cyanocobalamin. It is well-known that corticosteroids have serious adverse effects, including gastric ulcer, infection, diabetes mellitus, shock, thrombosis, and infarction. Sudden-onset sensorineural hearing loss at lower frequencies has recently been classified as an independent disease entity because of its good prognosis.3, 8 Although the spontaneous recovery rate is about 65% for all cases, 1 the rate is about 80% for the low-frequency type.3, 8, 9 This study was conducted to examine the effectiveness of cor ARCHOTO and grepafloxacin.
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The major prognostic determinants of well differentiated thyroid carcinoma as deter mined by this retrospective analysis were stage of disease, age, and histologic type, with less impact on survival shown for the extent of surgery and postoperative ther apy. Some reports support2-4 and others contradict these findings.3.5.6 Patients with large tumors four cm or greater ; or tumors showing extrathyroid extension or capsular invasion had signif icant impairment of survival compared with patients with smaller tumors and tumors that were intrathyroid and without capsular invasion. 2-4.6.7 odal metastasis at the time N of presentation mainly with papillary can cer ; was not associated with impaired sur vival in the small sample of 14 patients in this group. Survival was equivalent to that.
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