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Rationale. The PERG is arguably the only way to probe the activity of retinal ganglion cells. The PERG is reported to be altered in the early stages of glaucoma and may predict future visual field losses. We have developed a user-friendly adaptation of the PERG for screening and follow up of glaucoma, called PERGLA. Methods. The PERGLA is recorded simultaneously from both eyes by means of skin electrodes on the lower eyelids reference ipsilateral temple ; , in response to horizontal gratings 1.7 c d, 25 deg circular field, 95% contrast, 40 cd m2 mean luminance ; , alternating at 8.14 Hz. Signals are conventionally amplified and averaged. The actual test lasts 3 minutes two blocks of 1.5 minutes each ; and subjects are allowed to blink freely. The amplitude and phase of the component at the reversal rate are automatically evaluated by Discrete Fourier Transform. Deviations from age-corrected norms are expressed in SD units and visualized on a polar diagram. The internal variability of the response and a noise index are also simultaneously evaluated. Results. Normative data n 100 eyes ; have been obtained in healthy subjects aged 12-85 years. On average, the signal-toSunday.
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I, too, extend greetings for the New Year, and sincere wishes for a prosperous 2004. It promises to be an exciting year for all of us at VISTAKON as well as in the eye care profession. I very proud, and just a little intimidated, to step into my new roles as editor of ACUnews and Director of Academic Affairs at VISTAKON. Stan Yamane and George Mertz are two truly great men who have earned my respect many times over in my career. Together with Howard Purcell, this trio really personified VISTAKON over the past decade and more. It is an honor to find myself among these friends and colleagues. And I look forward to continuing and growing the relationships Stan, George and Howard started with my new colleagues, Dr. J. Pat Cummings and Dr. Derrick Artis. As Stan pointed out, our Professional Affairs team is brand new for 2004, which means we may not always have all the answers, as we will all be learning on the job! But with our experienced administrative staff of Janet Williams, Rene Orr and Sabrina Skinner, as well as occasional frantic calls to Stan and Howard, we'll strive to provide you with the best service ever. I look forward to hearing from all of you as the year unfolds, whether it's new ideas or for ACUnews, comments for our new Professional Affairs team, or feedback on our exciting new product, ACUVUE ADVANCETM with HYDRACLEARTM. Having been part of the team who brought this product to market, I very confident that you will find it to be lens you can't afford NOT to be fitting. Best wishes for a Happy and Healthful 2004. With warmest regards, Cristina.
Currently, Long Beach Memorial has been successful in aggressively recruiting registered nurses, says Byron F. Schweigert, PharmD, CEO of Long Beach Memorial and Miller Children's Hospital. But statewide, demand for RNs is outpacing supply by about 7 percent. The U.S. Department of Health and Human Services reports that number will grow to 10 percent by 2005 and 46 percent by 2020. Those numbers are frightening because registered nurses play a vital role in patient care, says Judy Fix, RN, MSN, senior vice president of Patient Care Services and chief nursing officer. "When there aren't enough RNs, " she explains, "hospitals have to close beds.
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Heart Study investigators. Description of the Framingham Heart Study data for Genetic Analysis Workshop 13. BMC Genet 2003; 4 Suppl. 1 ; : S2.
Isogenic genomic DNA gDNA ; from the E14Tg1A.4 129P2 ES male feederless ES cell line was used to amplify the homology arms by long-range PCR using a mixture of 1 10 Pfu Turbo polymerase Stratagene, La Jolla, CA ; and 9 10 LA Taq Polymerase Takara, Kyoto, Japan ; . All PCR fragments were cloned into pGEM-T-easy Promega, Madison, WI ; and sequenced. Fragments were then cloned into pBluescript used as the backbone vector for the final targeting construct. The components of the final targeting vector are shown in Fig. 1A. The diphtheria toxin A DTA ; cassette was excised from the pPGKneoDTA vector from Dr. Soriano ; and the ACN cassette from plasmid pACN Dr. Capecchi ; . The final construct was confirmed by restriction digestions and sequencing. Targeting construct linearized with SacII 25 g ; was electroporated into the feeder-independent E14Tg2A.4 129P2-derived ES cells. After selection with G418 200 g ml ; , 307 neomycin-resistant and mesoridazine.
Address: Contact Person: Phone: Fax: e-mail: www Address: Founded: Total No. of Employees: Of which in R&D: Registered Offices: Parent Companies: Subsidiaries: Activities in Export: A-1190 Vienna, Billrothstrasse 79a 81 Mr. D. Ljuhar + 43 1 320 + 320 vie19 bct.co : braincon 1992 1-50 ~10.
Parents Unit is out of range. Units are not set to the same channel, either both on channel A or B. Parents Unit located near motorized devices, fluorescent lights, television, etc. Units are too close to each other and metamucil.
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100, 000 for services and , 000 for reimbursement of expenses ; . The vote of the Board was seven to two with Ms. Truesdell abstaining and Mr. Wortham voting nay. The County Attorney will draft a contract for Travis and Schneider and bring it to the Board for review and approval at the next Board meeting scheduled for October 30, 2003. B. Motion 03.9-414 Moved by Mr. Wortham, seconded by Mr. DonCarlos, and unanimously approved that, the Board approve authorizing administration to enter into an agreement between the Harris County Hospital District and Houston Community Healthcare Centers, Inc. aka Denver Harbor Port of Houston Clinic for radiology and laboratory services. C. Motion 03.9-415 Moved by Mr. DonCarlos, seconded by Mr. Jackson, and unanimously approved, that the Board approve the Harris County Hospital District Draft Strategic Plan for Presentation for Public Feedback. D. Consideration of Approval to Utilize Community Health Choice CHC ; for Processing, Accounting and Reporting of Claims as the Harris County Hospital District HCHD ; Implements a Relative Value Unit RVU ; Payment Methodology for Affiliated Medical Services AMS ; This item was pulled. E. Motion 03.9-416 Moved by Mr. Wortham, seconded by Ms. Truesdell, and unanimously approved, that the Board approve that a six 6 ; month agreement with Ms. Beth Cloyd be implemented at a cost not to exceed , 000 , 000 professional fee plus expenses not to exceed , 000 ; for Project Management Services on the AMS RUV Implementation Project. XI. Executive Session At 11: 28 A.M., Chair Mary Spinks stated that the Board would go into Executive Session under Section 161.032 and Chapter 551, Texas Government Code, Section 071 and 072 of the Texas Health & Safety Code as permitted by law. She stated that the regular meeting of the Board would be reconvened at the close of the Executive Session and methadone.
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To counteract some of the effects of these drugs, other drugs such as bactrim and mesna are given days before and after the above drugs.
The management of brain tumors continues to bring new challenges for the treating physicians, and ongoing research is aimed at defining the biologic mechanisms of malignancy and developing new treatment modalities. Managed care policies and the need for cost containment make treatment decisions even more difficult, especially for elderly patients and methazolamide.
Phosphorylation by 30131% p 0.01 ; : the increase in phosphorylation was inhibited by the PKA inhibitors, myristoylated PKI 1 M ; and H-89 1 M ; , but was not affected by the PKG inhibitor, KT5823 1 M ; Fig. 3 ; . Selective activation of PKA by the cAMP analogue, cBIMPS 10 M ; , also increased PDE3A phosphorylation by 27826% p 0.01 ; , and the increase was inhibited by myristoylated PKI and H Fig. 3 ; . Direct -89 measurements of PKA and PKG activities in these muscle cells 23 ; have shown that, at concentrations of 1 M and less, PKI and H selectively inhibit PKA activity, whereas -89 KT5823 selectively inhibits PKG activity. Isoproterenol, like forskolin, stimulated PKA-dependent phosphorylation of PDE3A that was inhibited by myristoylated PKI but was not affected by KT5823 Fig. 4 ; . SNP, which selectively stimulates cGMP and activates PKG in these muscle cells.
| Mesna chemotherapy1. 2. 3. Haskell CM, ed. Cancer treatment, 3rd ed. Philadelphia: WB Saunders Co, 1990. Chabner BA, Myers CE. Clinical pharmacology of cancer chemotherapy. In: DeVita VT, Hellman S, Rosenberg SA, eds. Cancer: principles and practice of oncology, 3rd ed. Philadelphia: JB Lippincott Co, 1989. Bristol Laboratories of Canada. Ifex product monograph. Ottawa, Ontario; 1989. Brade WP, et al. Ifosfamide: Pharmacology, safety and therapeutic potential. Cancer Treat Rev 1985; 12: 1-47. Klein HO, et al. High dose ifosfamide and mesna as a continuous infusion over 5 days - a phase I II trial. Cancer Treat Rev 1983; 10: 167-73. Creaven PJ, et al. Clinical pharmacology of ifosfamide. Clin Pharmacol Ther 1974; 16: 77-86. McNeil NO, Morgan LR. The bioavailability of oral and IV ifosfamide in the treatment of bronchogenic carcinoma. Int J Clin Pharmacol Ther Toxicol 1982; 19: 490-3. Allen LM, et al. Studies on the human pharmacokinetics of ifosfamide NSC-109724 ; . Cancer Treat Rep 1976; 60: 451-8. Zalupski M, Baker LH. Review: Ifosfamide. J Natl Cancer Inst 1988; 80: 556-66. Cerny T, Margison JM, Thatcher N, et al. Bioavailability of ifosfamide in patients with bronchial carcinoma. Cancer Chemother Pharmacol 1986; 18: 261-4. McEvoy GK, ed. American hospital formulary service: Drug information 1993. Bethesda: American Society of Hospital Pharmacists, 1993. Kurowski V, Wagner T. Comparative pharmacokinetics of ifosfamide, 4-hydroxyifosfamide, chloroacetaldehyde, and 2- and 3-dechloroethylifosfamide in patients on fractionated intravenous ifosfamide therapy. Cancer Chemother Pharmacol 1993; 33: 36-42. Krogh CME, ed. Compendium of pharmaceuticals and specialties, 28th ed. Ottawa: Canadian Pharmaceutical Association and methenamine.
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1564-1800] Canongate Register of Marriages. 299 Lindsay, Catherine, indueller, and Alexander Hamilton, tailor 28 May 1720 Lady Christina, daughter to the Earle of Craufurd, and John Hamilton, Earle of Haddintoun, ane of the parochin of Tunynehame, mar. in our Kirk be Mr. John Hogg 13 April 1648 Christina, daughter of Robert Lindsay, tailor in Tranent, and Archibald Scott, joiner 21 July 1797 David, merchant in Edinburgh, and Jean Home, laufull daughter to the deceast Mr. George Home of Abbay of Saint Bathans 3 Mar. 1721 Elizabeth, and Archibald Bunten, tailler, mar. in the Church of Halyroodhous by Mr. Patrick Hepburne, minister p. 6 Dec. 1668, Tuesday, 26 Jan. 1669 Elizabeth, and William Craig m. 25 Sept. 1687 Elizabeth, in this congregation, and Mr. John Heggin, minister, mar. in the Church of Halyroodhous by Mr. Patrick Hepburne, minister p. 17, m. Monday, 25 July 1670 Elizabeth, ane of Edinburgh, and Donald Malloch m. 28 April 1646 Elizabeth, daughter of James Lindsay, flaxdresser, and John Pollock, stockingmaker 2 Feb. 1791 George, goldsmith, and Mary Morton, daughter to the deceased John Morton, shoemaker in Caltown 20 Feb. 1762 George, merchant, and Jean Lindsay 14 May 1774 George, wright, and Agness Blyth, daughter of David Blyth, shoemaker 9 Jan. 1792 Gilbert, servant to Mr. Alexander Hunter, indueller in Edinburgh, and Barbara Scott, servant to Lieutennent Matthew Stewart 28 May 1709 Ladie Helene, laufull daughter to the Earle of Craufurd, and Sir Robert Sinclar of Stevinson, in the paroch of Hadingtoun, mar. within the Kirk of Halyroodhous be Mr. William Colvill, minister at Edinburgh p. 6, m. Thursday, 10 Sept. 1663 Helen, indueller, and Alexander M'intosh, serjant in the North British Fusiliers 31 Aug. 1723 James, lintdresser, and Ann Ramsay, daughter to James Ramsay, brewer's servant 23 Nov. 1765 James, stockingmaker, and Margarate Henderson, daughter of James Henderson, weaver at the Sceens 28 Jan. 1800 Janet, one in North Leith, and Adam Brown, blacksmith, mar. in the Kirk of Halyroodhous be Mr. Thomas Hog p. 7, m. Wednesday, 31 Dec. 1651 James, in the paroch of Crawmond, and Agnes Strang, relict of the deceast John Smith, sometyme thesaurer of the Cannogate 28 July 1693 Jeane, ane of Edinburgh, and Johne Hay m. Thursday, 17 June 1647 Jean, and William Tweedie, in the paroch of Lamingtoun Sabbath, 8 June 1673 Jean, and John Hamilton, blewgoun 21 Oct. 1749 Jean, residenter, and Joshua Kers, soldier in Lord Charles Hay's Regiment, and Captain Burrow's Company 14 Sept. 1754 Jean, and George Lindsay, merchant 14 May 1774 Jean, daughter of James Lindsay, and William Chisholm, marchant 5 Jan. 1786 Jean, daughter of David Lindsay, printer in Edinburgh, and John Waddell, glover 20 Oct. 1790 John, merchand, ane of Edinburghe, and Marie Peiris, mar. in our Kirk of Halyroodhous Thursday, 16 Dec. 1647 John, souldier, and Marjorie Stewart, mar. in the Church of Holiroodhouse Thursday, 19 Nov. 1674 John, cordiner, and Allasone Porteous, servitrix to Thomas Hood, burges 27 April 1697 John, servant to ye Duches of Argyle, and Barbara Donaldson, daughter to Gilbert Donaldson, merchand in Edinburgh 12 Oct. 1708.
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The ifosfamide-urea and ifosfamide-urea mesna lyophilizate compositions of the present invention are intended to be reconstituted with common diluents, such as water for injection, usp, to provide appropriate solutions of ifosfamide andifosfamide-mesna for parenteral administration, preferably intravenous administration and methimazole.
| Spend a casual weekend filled with superb educational sessions, visiting with other herbalists, shopping among vendors with herbs, herb and gardening products, and more. All at a charming conference center in the beautiful Blue Ridge Mountains of western North Carolina and at an affordable price. The annual Wild Herb Weekend WHW ; , presented by the North Carolina Herb Association, brings together herb hobbyists, gardeners, and herb enthusiasts from across North Carolina and neighboring states. The WHW 2006 program will feature more than 20 educational sessions taught by herb and gardening experts for beginners and experienced herb enthusiasts. Several programs will include information on Scented Geraniums, the "2006 Herb of the Year" KEYNOTE SPEAKER Doug Elliott, nationally-known as a heartwarming storyteller and lyricist with a deep interest in the natural environment and our relationship to it, will delight us with his storytelling expertise. Doug has also been called an herbalist, ranger, humorist, folk doctor and myth maker yet none of these descriptors capture his energy, knowledge and charm. In addition to his keynote address, Doug will lead our Wild Herb Walks and present a workshop on making carbonated herbal soft drinks and tonics. Saturday Evening Keynote Address "Woodslore and Wildwoods Wisdom" Since humanity's beginnings, our connections with the natural world have defined us and made us who we are. Doug Elliott's stories derive from his unique life style as well as his deep interest in animals, plants and people. His keynote address will be infused with educational material and packed with songs, stories, anecdotes and lore about the people, plants and animals that share this world. This will be an evening of smiling, laughing and total enchantment! Whether he's extolling the virtues of dandelions, pontificating on poke sallet, picking up pawpaws, pondering the "nature" in human nature, or wailing out a jivey harmonica riff, storyteller, herbalist and philosopher Doug Elliott celebrates healing plants and Mother Nature with a collection of traditional and contemporary songs, stories and lore as well as outlandish personal narratives, truth stranger than fiction, and more than a few belly laughs. Educational Sessions We are fortunate to have Doug conducting two morning Guided Herb Walks and a Workshop on making carbonated herbal soft drinks and tonics. Please see below for more details. About Doug Elliott Doug Elliott, who lives in Union Mills, NC, has preformed and presented programs at festivals, museums, botanical gardens, nature centers and schools from Canada to the Caribbean. Notable events include the National Storytelling Festival in Jonesborough TN; lecturing at the American Museum of Natural History in New York, the Royal Ontario Museum in Toronto and the Smithsonian Institute. In addition, Doug has led ranger training sessions for the National Park Service and guided people though the wilderness from Maine to the Florida Everglades. Doug is the author of 4 books, multiple articles in regional and national magazines and several award winning albums of stories and songs. Doug Elliott is an herbalist, naturalist, basket maker and author. He has spent a great deal of time with traditional country folk and indigenous people, learning their stories, folklore and traditional ways of relating to plants. For many years he made his living gathering and selling herbs. In recent years he has performed and taught from Canada to the Caribbean. He has been a featured storyteller at the National Storytelling Festival in Jonesboro, TN and has conducted workshops and programs at the American Museum of Natural History in New York, the Royal Ontario Museum in Toronto, the Atlanta Botanical Garden and the Smithsonian Institution. He teaches regularly at the Gaia Medicines from the Earth Herb Symposium, the Green Nations Gathering and Omega Institute. He has trained rangers for the National Park Service and guided people on wilderness experiences from Down-east Maine to the Florida Everglades. He was named harmonica champion at Fiddler's Grove Festival in Union Grove, N.C and mesna.
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Member satisfaction with health care providers remains high, according to a fall 2007 report based on second quarter results of the Blue Cross and Blue Shield of Oklahoma patient satisfaction survey. More than 4, 600 members were mailed surveys about their experience with their health plan and health care provider. Surveys are used to monitor and improve the quality of health plan and provider services our members receive. Highlights of the results are listed at left and methocarbamol.
To SNP were not inhibited by methylene blue in the study by Zhou and Torphy 1991 ; , the elevation of cGMP by SNP was inhibited by this agent, which suggests that cGMP is not involved in this response. Recent studies in guinea pig airways have also suggested a dichotomy between relaxations to NO and accumulation of cGMP Lindsay et al., 1995; Mahey et al., 1995 ; . Studies in human airways have also yielded conflicting results. Thus electrical field stimulation of human tracheal tissue, under conditions that selectively elicit relaxations that are blocked by NO synthase inhibitors, increased the levels of cGMP. The increase of cGMP, as well as the relaxation of the trachealis, was inhibited by methylene blue Ward et al., 1995 ; . Gaston et al., 1994 ; also noted that NO donors and NO itself increased cGMP levels in human airways. They found, however, that although methylene blue blocked the NO-induced cGMP elevations, it had no effect on the relaxations, which again suggests that pathways other than, or in addition to, cGMP are involved in the NO response. A significant limitation in all of these studies was the lack of powerful pharmacological tools that could be used to study the soluble guanylyl cyclase system. Nearly all of the studies relied on methylene blue to inhibit soluble guanylyl cyclase, but this compound is a very weak inhibitor of soluble guanylyl cyclase and, moreover, possesses other activities, including generation of superoxide anions Wolin et al., 1991; Marczin et al., 1992 ; and inhibition of NO synthase Mayer et al., 1993 ; . Recently, however, a very potent and selective inhibitor of soluble guanylyl cyclase has been identified Garthwaite et al., 1995 ; . The compound identified in this study, ODQ, has nanomolar sensitivity against soluble guanylyl cyclase Garthwaite et al., 1995 ; . ODQ appears to be very selective for soluble guanylyl cyclase in that it was ineffective at concentrations up to 100 M against particulate guanylyl cyclase or adenylyl cyclase Garthwaite et al., 1995 ; . Nor does this compound inhibit NO synthase or produce superoxide anions Garthwaite et al., 1995 ; . These reports on the selectivity of ODQ for soluble guanylyl cyclase have recently been confirmed Moro et al., 1996 ; . This study found that ODQ did not inhibit particulate guanylyl cyclase or NO synthase and moreover did not interfere with the ability of an NO donor to release NO Moro et al., 1996 ; . Relaxations elicited by the NO component of the NANC relaxant system and by the NO donor SIN-1 were substantially inhibited by the soluble guanylyl cyclase inhibitor ODQ.
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