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Referenz 51 Neurologie, 11. Auflage ; Ballard PA, Tetrud JW, Langston JW. Permanent human parkinsonism due to 1-methyl-4-phenyl-1, 2, 3, MPTP ; : Seven cases. Neurology 35: 949-956, 1985 Seven patients developed chronic and severe parkinsonism after repeatedly injecting 1-methyl-4-phenyl-1, 2, 3, MPTP ; intravenously. Levodopa and bromocriptine controlled the symptoms; however, within months, five of the seven patients experienced dyskinesias or on-off fluctuations. Therefore, neither prolonged levodopa treatment nor progressive disease was necessary for on-off phenomena. Because the neurotoxic effects of MPTP seem limited to the substantia nigra, damage to this system alone may produce all the motor features of Parkinson's disease. MPTP differs from other neurotoxins in that it consistently produces a pure parkinsonian state.
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3498 Table 2. Itchiness among prevalent haemodialysis patients, by country, in DOPPS I versus DOPPS II Country Percent of patients reporting moderate to extreme itchiness pruritus ; DOPPS I 199699 ; France Germany Italy Japan Spain United Kingdom United States Australia New Zealand Belgium Canada Sweden 38 48 46 ; 426 ; n 1973 ; n 445 ; n 414 ; n 2268 ; DOPPS II 200203 ; 36 42 40 ; 488 ; n 514 ; n 1555 ; n 553 ; n 462 ; n 1444 ; n 430 ; n 443 ; n 464 ; n 446 ; 0.62 0.10 0.08 Male vs female ; Time with ESRD, 3 months vs 1.05.0 years ; Time with ESRD, 312 months vs 1.05.0 years ; Time with ESRD, 5.0110 years vs 1.05.0 years ; Time with ESRD, 10 years vs 1.05.0 years ; Ascites vs no ; Hepatitis C vs no ; WBC count, 54006700 WBC ml vs 5400 ; WBC count, 67018400 WBC ml vs 5400 ; WBC count, 8400 WBC ml vs 5400 ; Serum phosphorus, 3.5 vs 3.55.49 ; mg dl Serum phosphorus, 5.56.7 vs 3.55.49 ; mg dl Serum phosphorus, 6.7 mg dl vs 3.55.49 ; mg dl Serum calciumalb, 8.4 vs 8.49.5 ; mg dl Serum calciumalb, 9.5110.2 vs 8.49.5 ; mg dl Serum calciumalb, 10.2 vs 8.49.5 ; mg dl Serum ferritin, 100 ng ml vs 100399 ng ml ; Serum ferritin, 400800 ng ml vs 100399 ng ml ; Serum ferritin, 800 ng ml vs 100399 ng ml ; Belgium vs US ; Japan vs US ; United Kingdom vs US ; Current smoker or stopped smoking within prior year vs non-smoker or stopped smoking 1 year ; Lung disease vs no ; Neurological disease vs no ; Congestive heart failure vs no ; Serum albumin, 3.0 g dl vs 3.514.0 g dl ; Serum albumin, 3.03.5 g dl vs 3.514.0 g dl ; Serum albumin, 4.0 g dl vs 3.514.0 g dl ; Age, per 10 years older P-value.
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In the presence of flounder saline 1 mM SO2 ; , the 4 flux ratio determined from unidirectional 35SO2 fluxes 4 in Ussing chambers was approximately 20 to 1 the secretory direction. Figure 1 is a representative plot of PTC sulfate secretory response. Radiolabeled sulfate was added at t 0, and transepithelial P to L flux reached steady state at 1 h Fig. 1A ; . The addition of 1 mM methazolamide to paired culture mates at t 0 Fig. 1B ; reduced P to L one-half and had no effect on L to flux. Net fluxes calculated from the unidirectional fluxes in paired tissues typically averaged 136 22.3 nmol cm 2 h Because control transport rates in primary cultures varied, the effects of methazolamide on secretory P to L ; , reabsorptive L to P ; , and net and methenamine.
CYANIDE: The presence of cyanide was screened by Conway Diffusion. Positive cyanides are quantitated using spectrophotometry. The of quantitation of cyanide is 0.25 ug ml. Normal blood cyanide concentrations are less than 0.15 ug ml while lethgl concentrations are greater than 3ug ml. -- NO Cyanide detected in Blood.
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Appeared randomly distributed over the period of this survey and all the operators were experienced. Ovarian stimulation Inability to collect oocytes was not related to the amount of FSH used to stimulate the ovaries. This was overtly demonstrated by the six patients who received 10 75 IU FSH per day and yielded at least one oocyte each. In 31 72.1% ; of the collection attempts patients had two or fewer follicles 15 mm in diameter by ultrasound on the day of HCG administration or an oestradiol concentration 2000.0 pmol l and could therefore be considered poorly stimulated. Fifteen women 37.2% ; were 39 years of age and at least 12 30.2%: five patients had missing data ; had a non-ideal weight for their height i.e. BMI outside the normal range of 1925 kg m2 ; . the 17 cycles in which no pituitary suppressing drugs were given, six of the women 35% ; had a `natural' luteinizing hormone LH ; surge and therefore exact oocyte retrieval times were imprecise. However, in only one patient was it clinically considered that ovulation had already occurred. One patient did not administer her ovulating dose of HCG, confirmed by a circulating blood concentration 10.0 IU l. The 26 cycles in which pituitary suppressing drugs were used represented a rate of 0.83% of the 3136 such treatment attempts, a value not too dissimilar to the incidence of 17 1837 in non-suppressed patients. Treatment attempts Of the cycles reviewed in which oocytes were not collected 21 women had their failure at their first attempt. Of these 10 did not return for further treatment and another six stopped trying after a second treatment cycle in which satisfactory ovarian stimulation could not be achieved. Another two women had further failed ovarian stimulations, making a total of 18 42.9% ; of 42 women who were either lost to follow up or a subsequent chance of pregnancy via assisted reproductive technologies Table II ; . Twenty-four couples continued with treatment, between them having from one to nine attempts at conception using non-frozen embryos. Four became pregnant 16% ; . Discussion Oocytes may fail to be collected from follicles during assisted reproductive treatment for a number of reasons including the size of the follicles aspirated, failure to induce luteinization and the resumption of meiosis by exogenous HCG and poor technique by the operating surgeon or the scientist responsible 86 and methotrexate.
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208 Canongate Register of Marriages. [1564-1800 Gray, Helen, laufull daughter to Hugh Gray, indueller in the Pleasants, and James Sutor, servitor to John Litle, brewer 1 May 1708 Helen, daughter to the deceased Robert Gray, blacksmith in the parish of Foulis, and John Douglas, journeyman wright 6 July 1759 Helen, daughter to the deceased - Gray, sometime farmer in the parish of -, now resideing in Edinburgh, and William Pew, baker 11 April 1768 Helen, and James Morgan, ware sivemaker 25 Nov. 1768 Isabella, daughter to the deceast Dougall Gray, residenter, and James Young, weaver 14 Mar. 1719 Isabella, daughter to the deceast Dougall Gray, and James Young, weaver and indueller 23 May 1719 Isabella, daughter of John Gray, mariner in Leith, and John Palmer, mariner 30 Dec. 1799 James, in this congregation, and Issobell Henrie, in West Kirk parochin Sabbath, 28 Sept. 1656 James, and Issoble Urquhart m. 28 April 1646 James, and Margaret Brysone in Edinburgh Sabbath, 18 Jan. 1652 James, merchand in Canongate, and Elizabeth Shirrif, daughter to the deceast Richard Shirrif, merchand in Prestounpans 21 April 1722 James, cordner, and Janet Gray, servitrix to Thomas Veitch, surgeon 18 Nov. 1727 James, stockingmaker, and Elizabeth M'Kenzie, daughter to George M'Kenzie, gardner in W. Kirk parish 12 Jan. 1776 James, coachmaker, and Helen Black, daughter to John Black, weaver in Cullross 19 Mar. 1781 James, upholsterer, and Margratt Foord 10 July 1787 James, taylor, and Rosanna Gray, daughter of William Gray, residenter in Edinburgh 7 Aug. 1793 James, dyer, and Barbara Wood, daughter of Adam Wood, shoemaker in Lauder 24 May 1794 Janet, and John Chisholme, mar. in the Church of Halyroodhous by Mr. Patrick Hepburne, minister p. 9, m. Tuysday, 25 July 1671 Janet, ane of this congregatioun, and John Hamilton, ane of Edinburgh m. Tuysday, 27 July 1647 Janet, daughter lawfull to James Gray in Iron Mylne, and James Wilsone, smith m. 20 April 1695 Janet, servitrix to Thomas Veitch, surgeon, and James Gray, cordner 18 Nov. 1727 Jean, daughter lawfull to Gilbert Gray, schoolmaster, and James Scott, wryttar in Edinburgh p. 10 Mar., m. 5 April 1694 Jean, daughter of the deceased Robert Gray, and James Donaldson, in Peebells 21 Nov. 1791 Jean, daughter of Charles Gray, baker in Dudingston, and John Brown, smith 28 Mar. 1797 Miss Jessie, daughter to the deceased Alexander Gray of Overskibo, and James Townsend Oswald of Dunikeer, Esq. 30 Sept. 1769 John, hammerman in North Leith, and Dorathie Gyllar, mar. in the Colledge Kirk by Mr. Patrick Hepburne, one of the ministers at the Kirk of Halyroodhous p. 21 Feb., m. Thursday, 11 Mar. 1669 John, litster, ane of this congregatioun, and Bessie Purdie, ane of Edinburgh m. Tuysday, 24 Nov. 1646 John, in Cannongate, and Elspeth Craig in Edinburgh, mar. in the Church of Halyroodhous by Mr. Patrick Hepburne, minister p. 10, m. Tuysday, 26 Oct. 1669 John, cordiner, and Jonet Clerk, mar. in the Kirk of Halyroodhous be Mr. George Leslie p. 15 July, m. Tuysday, 14 Aug. 1655 John, servitour to the Earle of Sutherland, and Helen Mitchell, relict of umquhile Samuell Guthrie, merchant in Edinburgh 17 Dec. 1698 and methylcellulose.
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