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Following: reports that expression from the CMV promoter becomes attenuated with time, the possibility of immunostimulatory sequences contained within the CMV promoter, and adverse effects of Factor VIII production in cells other than in liver tissue. If further research concludes that this is indeed the case, there are other liver specific promoters and enhancers that could be utilized instead. An additional way to make gene transfer expression from a plasmid more efficient is to eliminate bacterial sequences from the plasmid. Bacterial sequences and cryptic expression of bacterial proteins can cause an immune response. Bacterial sequences can also reduce
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1. Knisely AS. Neonatal hemochromatosis. Adv Pediatr. 1992; 39: 383-403. Shneider BL. Neonatal liver failure. Curr Opin Pediatr. 1996; 8: 495-501. Knisely AS, O'Shea PA, Stocks JF, Dimmick JE. Oropharyngeal and upper respiratory tract mucosal-gland siderosis in neonatal hemochromatosis: an approach to biopsy diagnosis. J Pediatr. 1988; 113: 871-874. Vohra P, Haller C, Emre S, et al. Neonatal hemochromatosis: the importance of early recognition of liver failure. J Pediatr. 2000; 136: 537-541. Chiu MK, Davey AM. Neonatal hemochromatosis. Clin Pediatr Phila ; . 1997; 36: 607-610. Takeda Y, Ohya T. Sicca symptom in a patient with hemochromatosis. Int J Oral Maxillofac Surg. 1987; 16: 745-748. Ward-Booth P, Ferguson MM, MacDonald DG. Salivary gland involvement in hemochromatosis. Oral Surg Oral Med Oral Pathol. 1981; 51: 487-488. Blandford RL, Dowdle JR, Stephens MR, Walker DM. Sicca syndrome associated with idiopathic haemochromatosis. BMJ. 1979; 1: 1323. Hoogstraten J, de Sa DJ, Knisely AS. Fetal liver disease may precede extrahepatic siderosis in neonatal hemochromatosis. Gastroenterology. 1990; 98: 16991701. Shneider B. Genetic counseling in neonatal hemochromatosis. J Pediatr Gastroenterol Nutr. 2002; 34: 328.
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Recommended the installation of an `Actron' unit, model SCA27, cooling capacity of 27.0 kW, reverse cycle, ducted split system. This option is the most expensive, quoted at , 000 + GST including commissioning & labour ; . The air conditioning unit does not have any particular energy efficiency features, uses refrigerant type R22 which is an ozone depletion substance hydrochlorofluorocarbon HCFC ; . This type of refrigerant is subject to phase-out regulations. 5.2.2 Option 2 and nutropin.
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It pays tg adserti u In i Rpgister % T ut let ar senator o r conpru n n ntr JUCG a men ure to help VOTE FOR t i e firrifMs ini an assful hussl [, UL up from t h ? prot . nd inter TOWN, TALK Tl j s thu tand h\ ti n firnt-f an 1 rumosin , ome of the THB PBINTBH" fills t l a t-iA of n k in ij-riuulture t * H L H IOctol r b t ill tic l i t tun. t ? nt nnythmt, p t rnili Thi c c 11 tint! bs t l rt-\ U t ill ab ut tit. ssiy tht-\ art. AT THE COMING ELECTION 3 an unnnc a n tdm n i n fan tl tu n ntl u th m SQtr TIr j l i lind L\ O r tht. Vc t th farmers arp party T l i ir! tan 1 i j fui a chanj. In YOUR SUPPORT SOLICITED to one tunth d 1 uch uh 1 lnty t f ngn tnpd b tr .ir cnnsit-tmi t J ultur 1 int TL t ] for t ? C mdin l y t urgent riosem nt m folk who mal-t dSiin urn nfe m pnht c nu nttunpt to m ku thu puhl e sstJfare Tins e i t candi 1 ite" tell \ ht they tand on qu a tion Enl ghtnuf d puMic bought, tht"s Junt fill down and th c worship parts i I an "sotn op m n may c\t.ntuall ehang thi Mo t fulls want t3 1 p fair ind ORUL ai thi-'s darn plna rr til t t tins r t - r svh t r n unfa r leil the or kr , t thu farts L r tl-L farmt-r gpttmg there s 11 K change. Before this takes place * Stand by the party! Suppose hosvever * the farmers of New Jersey everybody always did this There of the East will themselves would not be much sense in holding elections. One election would be have to follesy the example of the Western agriculturists and take a enough * All the other elections would go the same way.forever af greater Interest in righting their wrongs and in electing officials ter if everybody always stood by own wlll stand by their interests * who -the party, for which they voted in 3 * Q * e-e * o -- that first eleetion * There svould bo The gift Of Bacigalupi Bfothers an uninterrupted ; nd perpetual con- to the town of Red Bank ought to trol of government by one party be largely used and largely - appreAnd one set of politicians; I t would ciated. The free use of an acre of be even worse than a monarchy * land for parking automobiles in the * i * business section of Red Bank Is a The independent voters who dont gift that ii ag unusual a i it usq stand by the party but who vote ac- fuh cording to their judgment never get any praise from the politicians and How long the public will have the orators * . The political luminaries use of this parking space Is not like to talk a lot about the people known * but if It is only for a year * standing by the party, but no one it will be a very worth-while contri ever hears them talking about the butioh. While full appreciation for party standing by the people. They this gift should he shewn * i t should holler a good deal about the neeeg not be forgotten that this is a temslty of being regular and of be- porary and not a permanent solulonging to some political organisa- tion of the parking problem * * w tion * The generosity of Baeigaltipi * * ' The independent voters who are Brothers hould cause no abatement net swayed, by such arguments need in efforts for the town to have park no praise * They have the satisfac- ing grounds of its very own * Either tion of knowing that they are the the Bacigalupi property e r some final arbiterg--the force t h a turns other property equally a s large er elections one w a y other * equally as central should be eh They cant be driven like a lot of talned * cattle and manipulated t s suit t h e The ordinance which the commls' desires of some grasping set of politicians * There is no feeling like sioners recently passed limiting the that of independence. Partisan time that automobilea can be sealsts may get temporary satisfac parked in t h business section has t i e party victories * but it is not been enforced and i t should not not the same kind of lasting satis- be enforced, now that this offer has faction t h a ail independent voter been made and accepted, Baciga gets from t h e reflection t h a lupi Brothers have. the right idea marked his own ballot instead of for improving traffic cendltlsns marking It according to the dictates That way is not t e drive folks off of eme political boss * the gtreet! by limiting parking- time * m hut to provide a place where autoThe independent voter Is a better mobiles can be parked * and mere intelligent voter than a Town Talk continued on page 16. ; partisan. Every political a c t for the betterment of the public has proceeded from the ' independent veteri * They can well afford to ignore the criticisms' of those who rant a t them because they are not regular partyites * They are voting for something more Important than party * They are voting for principles and conviction arid n e t because they want political jobs or want to curry favor with, political bosses * WEDNFEDVi CK i 0 ITT.
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